I do use integer scaling. That's what makes 1080p bearable on my 4K display, and not other resolutions that don't divide evenly into 4K.
An annoying quirk is that I have to use the Nvidia control panel specifically to get Windows to send a 1080p signal as otherwise, it will just upscale 1080p to a 4K signal. It makes no fucking sense to me why that would be the default but whatever.