One exception that does come to mind, is .Net Framework on x86. AFAIR that didn't use SSE or SSE2. (In x64 mode it did however, since those were part of the baseline for x64)
01b2086a 8975e4 mov dword ptr [ebp-1Ch],esi
01b2086d db45e4 fild dword ptr [ebp-1Ch]
01b20870 d95de4 fstp dword ptr [ebp-1Ch]
01b20873 d945e4 fld dword ptr [ebp-1Ch]
01b20876 d80dcc08b201 fmul dword ptr ds:[1B208CCh]
01b2087c d95804 fstp dword ptr [eax+4]
And that should be with optimization enabled, I didn't start it from the debugger.But clearly it has some support for using SSE2 when available, because it does use it for zeroing memory:
01b20884 0f57c0 xorps xmm0,xmm0
01b20887 660fd607 movq mmword ptr [edi],xmm0
01b2088b 660fd64708 movq mmword ptr [edi+8],xmm0