It's like running potentially buggy code - or an well-biased fuzzer -, but at massive scale, and code that can self-modify and self-expand. "Alignment" is just a way to describe aggregate statistics about their runtime behavior.
They don't need to be intelligent, or alive, or "more than token prediction engines" for this. They just need to happen to end up making the wrong API calls without the operator seeing it coming. No virus has a brain, yet they can be very bad for you.
I understand that some people get turned off by anthropomorpization or scifi language. Fine! But don't turn off your engineering brain over it.