500 people die annually due to acetaminophen poisoning, mostly from attempting to take too many painkillers which include both opiates and acetaminophen. The acetaminophen is included for the express purpose of "dissuading abuse."
Tylenol the worst thing to take with alcohol after binge drinking it's terribly hard on your liver.
It's worse for women who can't process ethanol ("alcohol") as well as men due to women's bodies producing less dehydrogenase which breaks down the ethanol.
From what I understand alcohol and acetaminophen (Tylenol) are processed by the liver in the same way so ingesting both overloads the liver, more so in women.
I think liver failure is going to be common in a few years in the 30-something crowd.
I'm not a doctor and not involved in any way in the medical field just a concerned citizen.
https://www.ncbi.nlm.nih.gov/pubmed/2248624 http://www.health.harvard.edu/fhg/updates/overdoing-acetamin...
So, it's probably just an education thing. Tylenol seems fine at what it does, and it isn't like people are misled. I bet you the label warns against mixing alcohol with Tylenol, and people really should know not to mix alcohol with other drugs.
I can't recall where I read it but I remember reading how a person should not use Tylenol even three days after drinking since the liver is still dealing with it. I'm not sure if that's true for any drink or just binge drinking.
College students who bing, take Tylenol, next weekend bing and so on are probably the ones who will suffer the most liver damage.
The liver is an amazing organ it's the only organ that can repair itself and regrow due to physical damage but not systemic damage.
The current understanding of paracetamol and alcohol is confused - some people think there may be a protective effect from the alcohol; other people think the combination may be more harmful than the sum of the paracetamol and alcohol; others think it's only a problem with pre-existing liver damage.
Aspirin is harmful to the stomach lining, and I personally would not like to take aspirin after heavy alcohol use.
(http://www.pharmweb.net/pwmirror/pwy/paracetamol/pharmwebpic...)
Really poor implementation though.
There are many good reasons not to abuse oxycodone. The government doesn't need to add to the damage of people who are only hurting themselves.
Unless he is pointing out that liver failure induced death puts an end to any addiction, I am absolutely denying that it puts a stop to abuse.
I usually take muscle relaxants (Soma) with Naproxen for back pain, and avoid the opioid pain meds or acetaminophen.
Even if your doctor knows all the drug interactions, he doesn't know the other stuff you're consuming like alcohol, grapefruit juice, over-the-counter painkillers, and so forth. See http://www.dailymail.co.uk/health/article-1158671/How-health...
Apparently I'm not the only one who feels this way. According to wikipedia: On June 30, 2009, a U.S. Food and Drug Administration (FDA) advisory panel voted by a narrow margin to advise the FDA to remove Vicodin and another painkiller, Percocet, from the market because of "a high likelihood of overdose from prescription narcotics and acetaminophen products". The panel cited concerns of liver damage from their acetaminophen component, which is also the main ingredient in commonly-used nonprescription drugs such as Tylenol.[8] Each year, acetaminophen overdose is linked to about 400 deaths and 42,000 hospitalizations.
Brief Google returns 31%. Still a large percentage but nothing like the number of people who die from prescription opiate abuse (the better part of 15K). Powerful drugs sometimes result in the death of user, news at 11.
I know it is hard for a lot of people to identify with drug users/addicts/fiends, so imagine we tried to apply the same sort of 'solution' to, say, speeding. Make all cars disable driver-side airbags once you go, say, 15% over the national speed limit. Speeding sometimes results in the death of the driver, news at 11.
How does that sit with you?
"Make all cars disable driver-side airbags once you go, say, 15% over the national speed limit."
I'll suggest a better analogy. People have to wear seatbelts/motorcycle helmets. Unfortunately this does kill some people but on the whole it does far more good than harm.
> They don't put acetaminophen in opiates to poison people
> natural check for abuse
The "natural check for abuse" is a threat of poisoning. If acetaminophen did not poison, it would provide no "check for abuse".
Seatbelts are not a deterrent to anything. Your analogy is terrible.