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Gambit-C has also been around since '88 and can compile to fairly portable C.

Probably been a decade since I tried compiling it for DOS, but I believe getting it up and running shouldn't be difficult.

Gambit-C 3.0 binaries are available at: https://gambitscheme.org/3.0/gc30-dj.zip (for DOS/DJGPP)

The other versions from https://gambitscheme.org/3.0/ are Windows or MacOS Classic binaries.

Needs a 386+ CPU, though.

What I remember from back in the day was XLISP.

That's going way back, and was portable enough to be used on a variety of operating systems. There was a package of it for the HP Integral!

An early version of Xlisp was used as the basis for Autolisp, but Autolisp wasn't updated to track Xlisp's capabilities. It's kinda like how Commodore BASIC was a nerfed version of Microsoft BASIC that Commodore licensed back in the 1970s and then never updated since to track later BASIC versions, just added a few commands here and there to support later Commodore machines.

It was a little disappointing to me given there were TurboAssembler, Turbo C, Turbo Pascal, Turbo Basic, and Turbo Prolog and that Borland had a trademark for Turbo Lisp that I don't think I ever saw an available version of that.