We've had vaccination/innoculation for centuries and people still don't accept it.

> To his credit, Dr. Lister crossed the Atlantic to deliver a lecture to a hostile American audience to try and convince them of his methods in 1876.

> Our own Jake Wynn argues that it wasn’t until the death of President Garfield in 1881 that the American public and physicians began to turn toward germ theory. His slow and painful descent from an assassination attempt was well documented and publicized at the time.

There is a difference between information transmission and it getting absorbed into the public opinion and understanding so much that a constitutional amendment would consider it. To go from Joseph Lister’s and Louis Pasteur’s work in the 1860s and think that politicians and the general voting public in the US passing a constitutional amendment that considers it in a handful of years just doesn’t make much sense.