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I don't think "destroy humanity" is in the eye of the beholder. The most clear interpretation is the extinction of the human race.

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Well if you go by total extinction, then even Skynet in Terminator doesn't count given that there were people left over to resist.

I don't think it's impossible to upset the balance of value in a Mansa Musa kind of way that can lead to black death levels of destruction though resource misallocation. Unlikely, sure. But with the wrong kind of people in the wrong place? Could end up pretty bad. We've built our society as a great filter that funnels sociopaths and psychopaths to the very top by selecting for lack of empathy, and now it's primed and ready to bite us in the ass.

Indeed at the time of skynet in terminator humanity was not destroyed yet. But it was on a clear path to destruction.

mindless idiots feel no need to procreate eventually due to brain rewards being fully hijcked. humanity destroyed in a few generations

As far as we can see in various societies it's actually the highly educated and prosperous people who feel no need to procreate.

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