I tried it and the experience was not great. I first enabled chrome://flags/#force-enable-webgpu-interop which did nothing. Next, I enabled chrome://flags/#enable-unsafe-webgpu which made some WebGPU demos work, but they all use my CPU's integrated GPU, which is worse than using no GPU acceleration at all. Next, I found out that there is a powerPreference: 'high-performance' option. It can be enabled with chrome://flags/#enable-webgpu-developer-features and I can now request a GPU with 'high-performance' power preference, although there is no way to check whether this actually selected the correct GPU, and it is useless to do it like that anyway, since no website actually sets this (experimental) option. Fortunately, there is the flag chrome://flags/#force-high-performance-gpu which should solve this, but it is not available for my platform. I have a fairly standard RTX 3060, but apparently, the most common GPU (according to the steam hardware survey) is not supported.

Unfortunately, Firefox does not work any better. After setting the flag dom.webgpu.enabled to true in about:config, a few WebGPU examples (e.g. https://webgpu.github.io/webgpu-samples/?sample=helloTriangl...) work, but many other examples crash the browser. And of course, Firefox can't select the correct GPU either.