Now, eight or nine figures, that's probably going to pass the threshold for special attention. As in, you might be required to go to the bank in person with photo ID in order to authorize the transaction, that sort of thing. But under 10 million U.S. dollars? Many businesses will handle those amounts monthly, and the bank is used to seeing them.
And someone else correctly pointed out that there might indeed be extra scrutiny on such transactions, at a level you might not always see, e.g. when Notch suddenly started receiving tons of money from Minecraft sales, PayPal flagged the account for special attention. But then they figured out it was legitimate, and allowed the money to go through. Personally, having been on the receiving end of credit card fraud (which I caught early enough that the bank refunded me the two fraudulent transactions, a total of $300), I'm glad that "this looks funny" gets flagged. It causes me more inconvenience than it has saved me money: every time I try to buy airline tickets back home (I live and work overseas) it's a large enough transaction that it gets flagged, and I have to call the bank and say "Yes, that large purchase on (airline) is legit, please let it through next time when I try again". But it saves me from being on the hook for $2,500 if someone were to get hold of my CC number again.
I'm certain receiving a lump six figure sum on my personal account would trigger a review, if only because the taxman wants to know about it.
Backend-wise, it's just different sets of flags. The infrastructure is the same.
I think generally speaking, there's two systems; the one is a scam / self protection system that disallows large transfers but the user can disable it themselves, the other is something that works after the fact that looks for things like money laundering and tax evasion, but these processes run nightly, yearly, or maybe even once a year. I'm half expecting a tax bill for some unreported crypto assets abroad, half because it's only a few hundred worth.