But with auto MDI-X, each device would notice "hey, I'm sending but not receiving anything," and would try flipping its Transmit and Receive functions around (transmitting on the RX pin and receiving on the TX pin). Since each device waited a random period before doing that, it was very unlikely (nigh-impossible) that they would both flip at the exact same moment. And if they did, the second interval would most likely not be identical either.
I'm simplifying a bit in the explanation above, but that's the broad strokes. And that's how my carefully-labeled crossover cables started gathering dust. (And then I realized "hey wait, I can just use these as normal cables now", and pulled them back out of storage and mixed them with my normal patch cables).