Fork Anubis. Slightly modify the hash function it computes. Deploy. Do not try to make your fork widely adopted. Do not even publish it.
You've just defeated ASICs and any craweler that's special-cased Anubis (currently all of them). If enough people do this, the only recourse they will have is either genuinely executing served js code like a real user or building some unholy pipeline that uses ai agents to compile it to a GPU kernel for every host.