Even for keys that aren't mnemonic, do you want undo to be ctrl + z or ctrl + the key closest to left shift?
Hence my original comment. I haven't had a problem with different keyboard layouts, since most of the keys that change are on the outer edge, nowhere near where the most common shortcuts are located (then again, I rarely type using QWERTZ).
> Even for keys that aren't mnemonic, do you want undo to be ctrl + z or ctrl + the key closest to left shift?
CTRL+Z, since that's what it's been since time immemorial, even on ISO keyboards. Consistency is king.
Example: What should the accelerator be, and how should it be displayed, if your "Exit" option is labeled 終了?
I checked VLC and apparently they use: 終了 (Q)
Even though "Q" doesn't necessarily make any sense to Japanese people who don't understand any English.
Similarly as an English speaker I would be quite confused if the shortcut key for exit was a totally different letter like P or something.