The fundamental problem with FIFA is the revenue body is also the sport’s standards and adjudication body. Split those functions, with one selling tickets and divvying up spoils, while a separate committee polices the sport, and you put aside a lot of the corruption issues unique to FIFA.
What would be better is if they can work together to root out the corruption, but as long as profitability is worshiped as openly as it is, it will tough to fight since money is so concentrated and it's now a kind of self-sustaining entity.
Other confederations are important for FIFA-internal politics (especially the African votes, Infantino's biggest group of supporters), but for fans and players the quality of the clubs matters far more. And that is geographically clustered
On the field, Brazil doesn’t appear to be most important these days.
Fewer than Argentina.
Fewer than Uruguay.
And yes, I acknowledge your cherry-picking was Libradores.
Brazil has the richest league in South America and thus like England its teams can buy better players.