The Sloppification of Peptides

It was a quote from Claude.

> corpuses (corpii)?

The Latin plural of corpus is corpora. It gets used a lot in linguistics articles, perhaps other fields as well.

No, and I don't think they're meant to fool humans.

We can't make that inference. Just because people use escalators doesn't mean that cars are relatively useless.

AI companies are data hungry, they likely use everything from books to the internet and chat logs.

The people who curate training data use all kinds of tricks, yes. They also constantly try new ideas and see what helps.

Btw, learning from your own generated data isn't necessarily bad, if you have an external source of validation. See how AlphaGo learned from self play for a simple example.

The vaaast majority of LLM training data is LLM generated.

Source: look at how good Chinese models are.

Not only for training, but for anything really.

I'd say at least 99% of all new youtube videos are AI generated video, whether taking snippets from other videos and voiceovering them, or just making entire fake personalities up from scratch. That number will raise to 99.99% soon.

There is no veracity to these videos, and within a year I'd say no one will ever be able to detect AI or not. This is exasperated by the fact that normal, real productions are being AI edited, and metadata or other non-visible means to detect AI or not will be meaningless.

Bluntly put, most people currently get their 'news' from Tiktok and Youtube. When I discuss current events with random, not-tech people, they all "believe" that if it's video, and on youtube or tiktok? It's real.

I cannot express how much the average Joe thinks, in their mind, "Something published on the Internet" is high in trust. I'm verbose, I talk to a lot of people, and there is an inverse relationship to computing skill, and Internet trust.

And using a computer to "do things" is not "computing skill", any more than driving makes one a mechanic, or ensures you understand a car engine.

I guess my point is, I suspect that the continued degradation of reporting, and news, conjoined with alternate sources being 'news sites', will continue to the point that "reliable source" is non-existent.

For example, imagine if every single post from a phone, such as "I see troops in City X' are seen as almost certainly faked. Or even, "I don't see troops in City X'. And if you think of it, certain sectors of society preferred the curated, more controlled news of the past. There may be attempts to purposefully destroy the credibility and believability of every and all independents on any platform.

Create a personality, have it trusted for months or years, and then show that its data was false. Doing this is easy with the tools today, doing it by creating one million such personalities with the same goal, is just as easy.

The end of truth for all is here now.

There is no point of trust now on the Internet. The cut off isn't just for AI, and training.

The cut off is for humans believing anything.

Yeah, France should try to export its culture sometime!

As someone from the UK, Techy, nerdy people can know, but normies don't.

Also, I'd add that gym bros definitely have heard of them, especially if they are familiar with steroids.

The GLP-1 drugs are probably the main cause of this. We have this amazing class of compounds that work really well, But are priced pretty high, at least considering lower UK wages.

So there is a big incentive to look at getting these much cheaper from China. You hear about this happening, and then you see the fact that these companies have big catalogues full of other peptides that are a crypto payment and a click away.

The only reason I know it is because I keep seeing spam for it on reddit.

Not every aspect of american culture makes it overseas and much less does now than used to 20-30 years ago.

I think peptides (and medicating yourself out of a hole in general) are a pretty uniquely american thing.

It's all over in Norway too. Anecdotally it is definitely more common than steroids already. I can only find statistics on the legal ones, but they show that 10% of all women in their 50's are prescribed the ones for weight reduction <https://www.fhi.no/he/fr/folkehelserapporten/samfunn/legemid...> (Fig 13).

Interestingly, snake oil gets it's reputation not because it is itself ineffective, but, it was because so many counterfeiters piled in selling cheapfakes, while simultaneously inflating cure-all claims. (citation, Smithsonian Magazine on Stanley Clark). Snake medicines are still used commonly in various types of Chinese medicine.

I have tried many forms of snake oil, have yet to find one that totally cures my pain. Oddly enough, I have found no modern medicine that totally heals my issues thus my reasons to focus on holistic solutions and non-traditional methods. Native Americans used natural remedies to heal and alleviate conditions. Who's to say their remedies are not effective. Same deal with acupuncture. Chinese have used it for centuries. I personally tried it a few years ago, when I had the money and it helped me. I find that holistic, non-traditional methods are helpful, especially when compared to opioids, pill-popping, etc.

Not really spamming, just in need of a solution. I've spend decades researching different literature for the many issues that I have. Not afraid to admit that I suffer from many issues, most of which are painful, uncomfortable, and limit my productivity as well as ability to make a living. Employers, it turns out, are clearly very hesitant to hire somebody with medical conditions. Suffice to say, that reading about a possible solution, new medications, treatment, has yielded little results, most things only promise pain management, no cures, at least for me hence my lack of patience with reading mainstream medical, journals that don't seem to cure anything, thus my preference for AI-based research, to the dismay of many here.

I'm not sure I'd agree that a "bay area peptide party" has any real, useful social benefit. Sounds like hell.

I guess "feeling like", sounds like a placebo.

From what I've read there is some real risks associated with using them. Sounds a bit like the marketing of steroids in the 70s.

My take on the peptides craze is it’s like random people started injected insulin because they have a hazy idea of it being helpful for something or other based on the word on the street but they aren’t sure about dose and also can’t be sure what they’re injecting is actually insulin or uncontaminated. They also aren’t diabetic.

> The real question is: Should you be putting novel, poorly researched and dubiously manufactured substances (which happen to be peptides) in your body via injection?

on one hand: no, absolutely not, hell no.

on the other hand: these people are voluntarily doing human sperimentation. things like this are going to happen anyway so we might as well collect the data (samples, effect etc). it's not much different from the safe needles initiatives.

So, chemical pollution and the destruction of our microbiome with excessive antibiotics cause a global obesity problem, and we pump more chemicals into the body to try to solve it.

Life out of balance, indeed.

BPC-157 was discovered in the late 80s, not really novel. As opposed to mRNA shots that everyone was taking happily.

You also wouldn't want to randomly inject yourself with insulin outside of medical supervision, because it can kill you pretty quick.

Injecting poorly-studied grey market peptides seems like a bad idea.

How is insulin a peptide? Insulin is a giant folded protein

"peptide" is just a category of chemical. Some of them do good things, some do bad things, some do nothing at all.

Anyone talking about "taking peptides" as a meaningful sentence is absolutely dismissible in the same way someone talking about "taking chemicals" is dismissible.

peptides seemed to have popped up about 10 years ago.... now we've got probably over 100 common peptides that are used for various things, here is a sample:

1) PT-141 is a peptide that releases sex hormone into the blood and literally makes you horny, and its primary use is for premenopausal women that have low sex drive.

2) PNC-27 is a peptide that supposedly attaches to the cell membrane of tumor cells and performs cell lysis (death) of the tumor cell, and it's supposedly affects many different kinds of tumor cells: breast, pancreatic, lung, colon, ovarian, cervical, and leukemia

3) Epithalon is a peptide that is noted for extending telomers on chromosomes, leading to longevity benefits.

4) MOTS-c is it peptide that in animal studies is shown to boost physical endurance and mimic molecular changes associated with training/exercise.

Ah yes... Ivermectin, very much like the crack epidemic. "It's for horses!!1!" "They do their own research!"

As with any substance, there can be use, and abuse. If you would have told people 30 years ago you use creatine, you would be stared at as if you inject steroids or growth hormone. Today it is in the supermarket, literally next to the protein bars. Throwing Ivermectin on the same pile as crack and heroin though.. :D

I am sure there are dozens (dozens!) of idiots who inject whatever they think it is for whatever reason, valid or not. Peptides is a craze, and it is also emerging here in the Netherlands, but as people have pointed out, lots of things are peptides, and lots of them seem to have significant health benefits, when used properly. Give it another 30 years... they will be next to the protein bars as well, once someone has figured out how to capture the profits.