For me, the huge one is that LLMs are currently bad at learning from experience. I don’t trust any kind of automatic MEMORY.md or whatnot; in fact I greatly prefer starting from a clean slate each time because the LLM’s baseline general knowledge is so good.
In terms of accuracy and “lying”, I don’t really see a huge difference. Most LLMs are unfortunately a bit sycophantic and over-confident, but you sometimes see that in people as well.