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Comment by woliveirajr | Hacker News Reader

Sildenafil [0] was synthesized to treat high blood pressure. Erectile disfunction was a side effect that raised much more interest.

Tadalafil [1] followed the path of Sildenafil about the phosphodiesterase type 5 (PDE5) enzyme inhibitor.

Help to live longer was the main objective since the beginning.

I invested heavily in ICOS when they launched, they had Bill Gates money and were looking for ways to extend lifespans and solve inflammation.

And all we got was another boner pill.

Lifespans and inflammation are ironically harder problems.

Yes, but we don't want medical science to go soft by focusing on the easy problems.

But the whole point of those pills is that it didn't go soft anymore!

thus this inuendo thread ended prematurely.

During your extended lifetime, wouldn't you like to be able to have a boner, though?

Picasso managed it all without these meds.

If you're saying it's easy, just be as good as Picasso, imma be real with you and say I'm not as good as Picasso.

....in bed

Quanity and/or quality of sex shows correlation with longer lifespan. Maybe this is a roundabout way to get there...

Healthy people have more sex I guess?

I do admire the fact that someone with a sense of humor at ICOS named the molecule TADA-lafil.

Well they extended something at least.

some lifespans are shorter when insemination never occurs.