Hotel laundry service tends to be quite expensive, but many hotels have a coin-op (or maybe an app these days) laundry room where you can do your own. That's very handy for underwear, socks, and casual items.
And some people for whatever reason think that everything you wear once needs to be washed before you can wear it again. Break out of that mindset. You can usually wear pants and shirts several times if they aren't sweaty and don't have food spills or something like that. Hang them up or fold them at night, maybe touch up with an iron if they are wrinkled.