Well, being harmful is the whole thing about tech. Economic and technological development happens through harming people, this is how society grows. Finding new and new ways of harming ever larger groups of people, forcing them to adapt.
And i don't even mean predatory ones, like Uber -> highstreet robbery, grabbing capital from taxicab medallion owners. This too, is progress, and makes lives of humanity overall, better.
Positive civilisational impact of an invention can be directly measured by number of people it put out of work. Harmful inventions usually don't do that. I can't think of anyone who lost a job because a nuclear bomb was invented.