They talk about "living at the bottom of the well" within our solar system (gravity well, that is). Mars effectively "divorces" from Earth (no kings / 1776, plus they need to be 100% self-sufficient), casually called "Dusters" presumably due to the Martian dust.
People working on the asteroid-based bases (in our "Asteroid Belt") are called "Belters".
Then also read: "The Moon is a Harsh Mistress" by Heinlein, where humanity colonizes "Luna" and have "Loonies" for relatively obvious reasons.
Both books delve a bit into the physiological changes but also the socio-political ramifications of humanity in space, and both are _excellent_ reads!
It's like moving to a desert.
I've watched a few documentaries and there are barely a handful of houses let's say in Death Valley. And Death Valley is a lot more hospitable than Mars.
To each their own, though, sure!
Mars with its -80 degC is much harsher desert than dirty industrial towns of Siberia.
In evolutionary theory is there a term for plateaus of differentiation?