I feel sufficiently old after having read South in this article. Good god what a throwback.
Django is hands down one of my favorite frameworks ever created, and the only one I still reach for in some contexts. For a lot of projects I use it to drive database migrations, and stand up an easy admin portal for others to use - then anything else is driven by an API layer written in (e.g) Rust.
I haven't had to care about Django's performance in years but still get to reap some of the benefits.