but anyone i have met that did Psychedelics more than a few times, permanently changed their brain chemistry in a way that was obvious. clearly they are doing some kind of unraveling that doesnt fully bounce back
ive barely taken them, but i watched many people change over years of use.
They might say the same thing about your lifestyle. The "reward structure of society" is highly abstract these days, arguably disconnected from "real life". You could say monks are disconnected from "real life."
This is a weird take, I think.
I've watched hundreds of people take them in great containers with great support. It's never a good idea to make big changes right away, but we take small steps to adjust our lives so we can actually be happy. Yes, even if that is less "productive". Why do we do the things we do anyways?
Psychedelics does however have longterm behavioural effects that are statistically significant and to some extent observable.
Using a definition of brain chemistry that defines brain chemistry at an atomic level you may assert that a change in behavioural patterns reflect a change in brain chemistry. But with such a definition anything that a person experiences does that.