It's about communism, World War 3, Israel _and_ Iraq _and_ Saudi Arabia _and_ UAE and other Middle-Eastern countries, it's about nuclear proliferation, it's about oil trade outside of the USD system, it's about China sanction proofing, it's about Taiwan, it's about terrorism, it's about Russia and many other things.
We usually don't act until the number of reasons to act reaches a threshold. We were slow to get into World War 2 as well. We wanted to act against Iran, but it was never the right time. Now with Russia, China, Venezuela and Cuba threatening war with their neighbors, the cost of not acting is too great if this network solidifies their cooperation against the US. Communists have been getting propped up all over the place, which is what we were seeing before World War 2, as communists believed they needed to achieve total global domination since they could not coexist with capitalism.
Iran has attempted to assassinate the US president multiple times as well as Netanyahu and carried out many assassinations around the world which it denied even when caught undeniably.
Russia got nukes, China got nukes, North Korea got nukes. There was every indication that Iran was aiming for nukes as well. You can't treat them like other countries that have nuclear programs, because most of those countries don't comingle with such bad actors. Similar to the communist party that wanted to control the world, Iran also has a radical group that wants to bring about the apocalypse to resurrect their prophet.
Russia also attacked Ukraine, Iran attacked Israel, but Venezuela was also going to attack its neighbor and Cuba was expanding its interference inside the US. You don't hear much about it, but it was important. It lines up with one of China's strategies to soak up US attention with crises to open up a window to take Taiwan.
If you are asking what actual information the US is acting on and what the underlying reasoning is, THIS is actually the reason. The details are vast and this is a massive abbreviation and some I haven't even mentioned even though they're relevant. People will link you to random junk, but every country has thinktanks and policymakers who get together and decide what is important for the country to act on. Who decide what the threats are and where a country's energies are best spent. These are the actual reasons. It's not simply "Israel" this or "Israel" that.