I disagree, and I believe that the complete stagnation of GUIs is due to ignoring this.
There is no good reason why a GUI system isn't:
Description->Pack->Apply events->Generate assets->Render assets.
At each point you reify the result into an artifact that is everything the next stage needs. This has a couple of nice properties. One property is that everything is deterministic and testable. Another property is that after the pack and apply, everything is now embarrassingly parallel. Another good property is that you have an artifact that the accessibility people can latch onto before you bury it under pixels.
That would be a very functional way to deal with GUIs.
However, we continue inheriting properties and single main threading everything like we're still on 33MHz machines with 8MB of RAM.