I don't think infinite customizeability is a problem. Poor default configurations are the problem when you build in the ability to customize.

The idea is that the user should be able to be productive more or less immediately after installing the software, and then incrementally customize it as they discover they have different needs than the defaults give them.

A lot of developers/companies forget the first part, and ship something that requires a team of consultants six months to set up before anyone can do anything useful with it. Of course no one wants that. (Well, except for the highly-paid consultants.)