The author's work seems really useful for detecting spam. There are some people / bots who post a lot of specialist content. They only ever post links to content on domains that pay when visitors click links. These domains have a lot of ads. There's no other interaction on the site.
_NOT SAFE FOR WORK_:
This user (http://www.reddit.com/user/walfa2) only posts content from sites which pay when viewers see the images. The domains have heavy ad content, with popups etc.
Here's an example domain:
(http://www.reddit.com/domain/img1.picfoco.com/)
Once you find one user you can find a bunch of these domains, and the other users posting to those domains, and thus find a few more domains.
With a bit of tinkering you could should a colour coded chart of spam domains; of users that only post content from those domains; and users that never make replies but only make top level comments.
That could be run once a week and (with human oversight) used to remove content which is not good for reddit.