Speaking of finetune, currently a common practice is LoRA over bnb 4-bit base model, but I think it's time to replace bnb with GGUF as the base model format. GGUF is actively supporting new model architectures and more aggressive quantizations.

I've made some proof of concept in https://github.com/woct0rdho/transformers5-qwen3.5-recipe . We can finetune Qwen3.5-35B-A3B in 16 GiB VRAM, and DeepSeek-V4-Flash (284B-A13B) in 90 GiB VRAM, without CPU offload. This works well on unified memory machines like Strix Halo.

Even so, larger models like Kimi-K3 still require multiple GPUs and nodes, and there are a lot more to do compare to single-GPU training.