Inside of Reddit itself? Not with the tools we're given from Reddit. We know Reddit has internal tools to block spam/bots, so I believe what we see is the most sophisticated ones (they're not too sophisticated mostly, but they're not the zero effort bulk spam that reddit catches easily).

Something that would make things far easier for mods would be if the posters hashed IP was shown/made available to mods. Thats mostly for more localized bad actors/astroturfers and not large spam/scam rings with proxy networks.

Things we've done that have made a difference with the tools we've got from Reddit:

1) we don't allow new accounts or ones with negative accounts to post in our subreddit

2) any posts that match criteria or hit the front page are automatically put in a mode where you must have a positive subreddit karma over a threshold to post. This helps filter out brigading and low effort shit posting from front page plebs

3) we're using a reddit app that allows us to remove posts from people that have posted in identified subreddits. Right now we're just experimenting with this and we're in a data collection mode, but we can see that the people its catching (while some of our most prolific posters) are also some of our most problematic posters, so I think we're going to go from data collection to just straight up having the bot remove comments from people that post in those troublesome subreddits.