Mushrooms are not quite the same, but give you more intensity control (and are much shorter duration). And legally there is ketamine therapy.

I'm not sure if it'll completely remove the cortisol issues I have. This feels biological, maybe due to early traumas. Are psychedelics supposed to fix these? I thought it was more for depression than always-on vigilance.

Removing all real dangerous stressors (like work and house woes) would really help. I tend to be a lot more tolerant of less sleep while on vacation. That said, I spend a lot of money and time finding quieter hotel rooms or airbnbs.