A much better game is Bartok (sometimes called Bartog) - it starts out as something approximating Uno[1]. Each time someone wins, they make a rule.
Playing it with Mathematicians/CS types is brain-hurty (think mod-13 arithmetic and prime numbered cards behaving differently).
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[1] Some of the different rules:
- If you ask a question, you get a 1 card penalty
- If you have one card and don't say "bartok", you get your hand made back up to 7.
- We played with a bunch of broken decks all smushed together, so you couldn't count cards.