> This paper is a review, meaning it synthesizes and interprets existing research rather than presenting new experimental data. The authors themselves note that current visual tests for susceptibility to discomfort are subjective and poorly standardized. They also acknowledge that the proposed mechanism (that discomfort is the brain’s response to overwork) has not been fully tested, particularly the hypothesis that colored tints reduce discomfort by steering visual stimulation away from overactive brain areas. The relationship between the brain’s excitatory and inhibitory chemical signals and visual discomfort also remains, in their words, “unsettled.” Several key research questions are flagged as unresolved, including how to best quantify the real-world impact of visual stress on people’s lives and how to objectively measure susceptibility.
Flickering lights are about the only thing I saw in here that seem like they'd be a problem in the long term. Everything else your brain just adjusts to over time and stops noticing. Maybe the first few days in an office with bright colors would be slightly distracting, but after that you just stop seeing them. I would guess that a lot of the studies they reviewed probably tested people's reactions to these things when they saw them one time, not the hundredth time.