Claiming that "information" is the underlying basis of the real is the same as effectively saying that "stuff" is the underlying basis of existence. It's essentially Platonism. It is not informative. What is informative is the operational use of the mathematical concept of information as defined by Shannon to understand real things or to structure theories. But this is a very different thing than identifying a substance that exists, independently of us in the universe. This "making real" of what is ultimately a mathematical abstraction is precisely reification.