Isn't Q8 way overkill these days? I see many graphs showing Q4 or Q5 having less than %1 deviation. Nvidia's NVFP4 Qwen quantization should be even better due to its better training methods.
I'm not aware of any great benchmarks that work by giving it a live agentic harness and a number of realistic tasks that take most of the context window to accomplish and evaluate success rate and tokens to completion... but that's what you'd really want to use to judge different quantization levels.
And for MoEs, very small amounts of loss can mean you're flipped to entirely different experts (this is also a problem more broadly with numerical stability issues too).