My understanding of the Shahed's is that they are relatively simple. They can be programmed with a certain destination and then have some basic image recognition that allows them to "choose" exactly their target based on computer vision, e.g. the shape of a building or radar station. So in that sense, they are autonomous. To my mind, they are more cheap precision missiles (more like a tomahawk) than an autonomous drone.

Predators are a whole different beast. They are semi-autonomous airplanes, that can be controlled by satellite or AWAC or whatever. Almost certainly with the ability to loiter or escape if they lose contact with their controllers