It will work for documents and the most simple TODO apps. It actually will not work for anything useful. There are a number of security policies in place explicitly to prevent things in file:// from accessing features available over real HTTPS. You will not have access to anything that requires a network connection, local storage, location services, WebRTC, etc. This is why things like Electron exist and why experiments like Active Desktop, HTA, the thing linked to in this article, that other project that had the same name as this one, and Adobe AIR were tried.