The honest way to say this is that Fable is not useful for bio-related work. The author is working on processing RNA sequences and similar biology tasks, and Fable's classifier has a hair trigger on those tasks.
It's like saying well a scalpel is used for medical reasons, sure. But manufacturing scalpels is metalworking, not medicine.
> salmon is a wicked-fast program for highly-accurate, transcript-level quantification from RNA-seq data. It pairs a fast mapping stage — selective alignment, or alignment-free sketch mode (--sketch) — with a massively-parallel statistical model (EM/VBEM over equivalence classes) to estimate transcript abundances. You can give salmon raw sequencing reads, or regular alignments to the transcriptome (an unsorted BAM), and it uses the same inference engine either way.
It is way worse than that. Try "How does digestion work?" and you will see "Fable's safeguards flagged this message". It's a stupid rate of false positives.