Behavioral patterns are a much better target.
If your cheats make you play like a legit player, who cares? It's the same as in the gym. People are bothered by people who look like Ahnold, and still can't lift one plate. Not the fattie who takes t to look like a normal person.
I think that's the spirit of VAC.
The only issue is it can't —or won't— detect people helicopter–hopping no–scope sniping around the map or terrible players who shoot you in the face every time in 12ms.