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Comment by janalsncm | Hacker News Reader

Before the reactions to the headline get too out of hand, the article says the study couldn’t rule out that obesity and diabetes might drive this change. Occam’s Razor leads me to lean on this more than any other exotic explanation.

Of course, PFAS and microplastics aren’t great for sperm health, but neither were leaded gasoline and DDT before they were curtailed.

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Also, it's highly person dependent.

I'm an obese american (lost 10% of my body weight in the last 7 months, so almost not obese anymore) who is 30+, but my testosterone has measured between 850 and 1400 in the last 7 months.

That probably helped with my weight loss, but I have a full head of hair still and am somewhat likely to keep it.

We'll likely spend longer measuring what the hormonal effects of PFAs and microplastics are than we'll have pfas and microplastics to deal with.

Good point. Age and obesity are the strongest correlates with low testosterone. Increases in sedentary lifestyles probably aren't helpful either, but not clear if that is anything other than a proxy for obesity

I’m pretty sure other experts are also saying that it’s due to a different way of measuring levels.

Which means, given GLP-1s, we should see a reversal in the next few years.

Random aside: is there a correlation between GLP-1 and vaccine acceptance? As in, given enough time, would one expect to see an obese, diseased, low-T population concentrating in on itself?

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