Anyone using these small chips for hobbyist purposes probably should look at the more fully featured MSPM0-L line or MSPM0-G lines. Still Cortex-M0+ and in the sub $2 market... But hobbyists probably don't see much cost benefit below that (how many MCUs are you buying anyway??).

The L line and G lines have better ADCs, Comparators, better connectivity, and some of them even have on board OpAmps.

Tiny chips have a use of you are tying to build the absolute smallest devices. But hobbyists don't have the equipment to comfortably build things of this size.

Sizing up to VQFN packages and 0603 passives makes more sense for the typical hobbyist.

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As far as how a professional would use this, there are plenty of good uses of chips inside of cables or other kinds of smarts. Like a chip controlling a bunch of LEDs for example, based on voltage measurements elsewhere (there is a 12-bit ADC after all, which means you have rather solid voltage sensing from a few pins).

Basic voltage comparisons + math + crude timer and then a few pins for in/out gets you to a lot of useful projects. Albeit dumb ones. I dunno why anything needs to be this small in particular though.