Javascript doesn't have structs. The idea is that you have data on one hand and you have type witness about that data on the other hand. Type witness is something for the type system. But here you encounter the limits of structural typing versus nominal typing, because structural typing isn't able to witness that directly.
In sufficiently strong nominal type systems, I can hide the constructor for an EmailAddress type (as in: nobody can just construct an EmailAddress type). In Haskell speak, I can then export a function parseEmailAddress = rawString :: string -> EmailAddress.
The function parseEmailAddress is the only place that has access to the constructor. Which means that the only way to turn a string into an EmailAddress is by calling parseEmailAddress.
Note that at runtime EmailAddress is just a string. The boundaries live in the type system, not on the value level.
A structural typing system (as in TypeScript) does not enable that, it forces you to turn EmailAddress into something else than just a string.
Are you confusing Email vs EmailAddress? I think that in many cases people would prefer EmailAddress to be represented as a dumb string at runtime. But if you don't, you will easily find other examples where you have 2 structurally similar types, that you don't want to mix up.