This article on Douglas Crofut [died 1981] implies that there were several.
"His death was the first of its kind in the United States since the 1940s, when radiation deaths occurred during the Manhattan Project at Los Alamos, New Mexico."
https://en.wikipedia.org/wiki/Douglas_Crofut
It turns out that there were two Manhattan Project fatalities, one in 1945, and one in 1946.