This bug comes from a programmer trying to fix one problem - users press Control S and get a save dialog - by altering some fundamental and bug-prone behaviour.
Imagine the damage programmers could do if they had more options to meddle easily! They have low-level APIs if they need them to hook keys. Best leave it at that.
Meanwhile, there is the accesskey attribute in HTML to let you customise shortcut keys: https://developer.mozilla.org/en-US/docs/Web/HTML/Reference/...