AFAIK there was a Lyme disease vaccine, but was discontinued, probably because it wasn't effective enough, I don't remember the details.
This is key paragraph from the link:
> The effects of vaccination on human behaviour presented yet another important uncertainty. Lyme vaccination, although it provides incomplete protection, may make individuals less likely to limit their exposure to ticks, which might actually increase their risk of Lyme and other tick-borne diseases (e.g. ehrlichiosis, babesiosis and Rocky Mountain spotted fever).
That was a very half-assed attempt. Hopefully a better one is coming soon.
The "cautionary" part of the cautionary tale referred to in the article title is that a working vaccine was retracted mainly due to unfounded fears
e.g from the article summary "Just 3 years later, the manufacturer voluntarily withdrew its product from the market amidst media coverage, fears of vaccine side-effects, and declining sales. This paper reviews these events in detail and focuses on the public communication of risks and benefits of the Lyme vaccine and important lessons learned."
The "public communication of risks" not the actual risks.
Isn't it more because meds are cheaper to test on animals and liability is much lower?
But prions were the cause, and those are slow acting.
The new, safer vaccine is only recommended if you're going to Japan or surrounding areas, and planning to going outside the city.
Humans generally aren't vaccinated for Rabies either, unless you are e.g. a veterinarian who might have a higher chance of exposure to it.