It's easy to find counterexamples: the entire science of pharmacology is based on macroscopic effects that often lack a fundamental understanding of the underlying mechanisms of action. Psychopharmacology is the extreme example. Often, the fact that a drug worked made scientists investigate and discover the mechanism behind it, but for many drugs used every day by billions it's still a mystery, or it's understood only in very broad terms.

So what will you do if the doctor prescribes you an LLM-vibecoded drug that nobody understands how it works, yet it cures some deadly affliction with close to 100% efficacy?

What if, say, these incomprehensible math results lead to a revolution in quantum physics which unlocks chip topologies that are orders of magnitude faster than human comprehensible designs?

Would the high priestess of human reason pass her divining rod over such chips or life-saving drugs and reject it as the work of the AI devil?