Personally I'd use memcached or some equivalent for strictly cacheing, and then bring on Redis with persistence if you need its data structures for e.g scoreboards.
At $WORK we never imported either, our cache layer for slow operations keeps its data in both the filesystem and a db table (used as a k/v store). The database helps coordinate thundering herd problems - this operation is being calculated by another thread, so just wait for it. Reads from the same server just hit the filesystem, and reads from another server hit the db once and then keep it in the filesystem. We could change the fs layer to memcached but so far it's working great.