Personal computing in the sense of actually controlling our hardware and software will be killed (or rather degraded) by government regulation and platform oligopolies.
I feel the same. But at the same time the generalization of laptops (with custom motherboard, and soldered parts) and smartphones (custom SoC) means this is already a niche thing. Gamers were the last mass market for upgradeable modular deskops, but a sufficiently long hardware drought would most likely make game editors way more resource conscious, which may kill this niche entirely.