looks like I was wrong, but here is the de-facto standard I was relying on over the years ;-). Not that I've memcpied many structs to file directly btw. http://www.catb.org/esr/structure-packing/
In practice, C doesn't do any padding shenanigans, but C++ does (but only for non-POD structs, and then you discover there's several slightly different definitions that mean basically "POD", so have fun predicting which one is the one that actually matters for your use case).
C++ "standard layout type" is the modern equivalent of "POD" I think.