I've noticed people's "computer literacy" varies dramatically based on the applicability of whatever they're trying to accomplish to their personal desires versus work.

Being a bit hyperbolic: An update moves one pixel out of place in a line-of-business application and helldesk calls roll in from core-dumping end users who simply can't fathom how to use the software anymore. OTOH, big streaming video or shopping service revamps their UI and the end users seem to have no trouble continuing to use company resources to play videos, shop, etc.

Edit: I have no doubt many large websites have better UX resources, as compared to LoB apps, but user motivation plays a big part.