I'm fairly sure languages such as Lisp and SmallTalk would be much more widespread today if the industry wasn't told what to use by clueless people driven by profits.
Check out the list of EIGHT GTK+ bindings for Common Lisp: http://www.cliki.net/GTK%20binding
And yet, the last time I attempted to write a trivial GUI application using GTK and CL, I could not find a single usable library. I tried four and they were all unusably broken on my platform. (This was some years ago. Clearly at least four more implementations have come around since then.)
I think this is a step in the right direction. If the XKCD comic is true that every generation produces a handful of lisp hackers, I hope this is the generation that looks to Quicklisp as a foundation to build a modern, consolidated set of batteries.