In a void* function prototype, whatever network code or gnarly dependency is all shielded behind a compilation unit. If you make it a template function the compiler will have to (re)process a lot of code. You could make the interface templatized in a header file and have the actual implementation use void * or char * pointer. That would recover good compiler performance.
I don’t think span provides much if any safety for the implementer of the library function. I’m also not convinced it’s more ergonomic for the caller.