Consider Todd Akin’s comment: "If it’s a legitimate rape, the female body has ways to just shut that whole thing down." While "legitimate rape" ended up being the colloquial reference that got hammered, what was so utterly offensive was the second part of the sentence. Implying the female body had some sort of magical spermicide. It's not just insensitive, it's scientifically ignorant. There are a lot of reasons why almost 2/3 of college students and recent college grads voted for Obama, and one of them is because of this complete idiocy that Republicans spew.
At the "Family Values Summit" earlier this year, Rick Santorum said, "We're never going to be the party of smart people." If you’re not the smart party, what are you? The party that claims the HPV vaccine causes retardation? The party that considers evolution a myth? Sure, but then you won't be the party with constituents that embrace science and technology.
Sure, they can throw money at the problem. Even if they intellectually objected with the platform, lots of engineers would work for the Republican party if they paid enough. But successful political campaigns are all about connecting a widespread media message to the individual visceral feelings of voters. If your staff has no idea who that voter is because they aren't actually one of them, then you're not going to have the same quality of campaign.
I don't think all is lost for the Republican party. For an example off the top of my head, it would be very easy to philosophically adjust their stances on "economic freedom" to support reforms to copyright and patent law. But until then, Rick Santorum is right. They won't be the party of smart people. Which means they won't be the party that has smart technology talent helping them run campaigns.